Material Information- (Supplemental Announcement of Material Information on August 6, 2026) Announcement of the newly appointed Chief Business Officer
1.Type of personnel changed (please enter: spokesperson, acting spokesperson, important personnel (CEO, COO, CMO, CSO, etc.), financial officer, accounting officer, corporate governance officer, chief information security officer, research and development officer, internal audit officer, or designated and non-designated representatives):Chief Business Officer
2.Date of occurrence of the change:2026/09/10
3.Name, title, and resume of the previous position holder:NA.
4.Name, title, and resume of the new position holder:Chi-Kai Lai / Executive Vice President and Chief Business Officer/ Cycle Pharma Chief Commercial Officer
5.Type of change (please enter: ”resignation”, ”position adjustment”, ”dismissal”, ”retirement”,
”death” or ”new replacement”):Newly appointed
6.Reason for the change:Newly appointed
7.Effective date:2026/09/14
8.Any other matters that need to be specified:The Board of Directors, at its meeting held on August 6, 2026, resolved to appoint Mr. Chi-Kai Lai as the Company’s Executive Vice President and Chief Business Officer to strengthen the Company’s global business strategy and operational footprint. The effective date of the appointment of the new Chief Business Officer is September 14, 2026.